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NFIA Mouse anti-Human, Clone: OTI4G8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF811215

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.Specifications
NFIA | |
Monoclonal | |
Unconjugated | |
NFIA | |
BRMUTD, CTF, NF-I/A, NF1-A, NFI-A, NFI-L | |
Mouse | |
Affinity Chromatography | |
RUO | |
4774 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI4G8 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q12857 | |
NFIA | |
Human recombit protein fragment corresponding to amino acids 200-509 of human NFIA produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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