NFIA Mouse anti-Human, Clone: OTI4G8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811215

Catalog No. 50-167-0527

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Specifications

• Antigen: NFIA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NFIA
• Gene Alias: BRMUTD, CTF, NF-I/A, NF1-A, NFI-A, NFI-L
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4774
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI4G8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q12857
• Gene Symbols: NFIA
• Immunogen: Human recombit protein fragment corresponding to amino acids 200-509 of human NFIA produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1