Invitrogen™ NFIA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568980

Catalog No. PIPA568980

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%.

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Specifications

• Antigen: NFIA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFIA
• Gene Alias: 1110047K16Rik; 9430022M17Rik; CCAAT-box-binding transcription factor; CTF; KIAA1439; NF1A; NF1-A; Nf1l21; NF-I/A; Nfia; NFI-A; NFI-L; Nuclear factor 1 A-type; nuclear factor 1/A; nuclear factor I A; nuclear factor I/A; TGGCA-binding protein; Unknown (protein for MGC:128467)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18027
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q02780
• Gene Symbols: NFIA
• Immunogen: synthetic peptide corresponding to a region of mouse NFIA.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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