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Invitrogen™ NFIB Polyclonal Antibody
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Catalog No. PIPA528299
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100 μL
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PIPA528299 100 μL
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Catalog No. PIPA528299 Supplier Invitrogen™ Supplier No. PA528299
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: nuclear factor I/B tansfected 293T cell, mouse brain. Predicted reactivity: Mouse (99%), Rat (100%), Xenopus laevis (95%), Chicken (97%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFIB
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene NFIB
Gene Accession No. O00712, P97863
Gene Alias 6720429L07Rik; CCAAT-box-binding transcription factor; CTF; E030026I10Rik; HMGIC/NFIB; NF1-B; NF-I/B; Nfib; NFI-B; NFIB2; NFIB3; NFI-RED; nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I B; nuclear factor I/B; olfactory epithelium nuclear factor I-B; TGGCA-binding protein
Gene Symbols NFIB
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human NFIB. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18028, 4781
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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