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Invitrogen™ NFIX Polyclonal Antibody
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Catalog No. PIPA597211
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100 μL
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PIPA597211 100 μL
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Catalog No. PIPA597211 Supplier Invitrogen™ Supplier No. PA597211
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AYFVHTPESG QSDSSNQQGD ADIKPLPNGH LSFQDCFVTS GVWNVTELVR VSQTPVATAS GPNFSLADLE SPSYYNINQV T; Positive Samples: A-431, Mouse brain; Cellular Location: Nucleus.

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFIX
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene NFIX
Gene Accession No. P70257, Q14938
Gene Alias CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; KIAA1439; MRSHSS; NF1A; NF1-A; NF1-B; NF1-C; NF1-X; NF1-X1 protein; NFI; NF-I/A; NF-I/B; NF-I/C; NF-I/X; NFIA; NFI-A; NFIB; NFI-B; NFIC; NFI-C; NFIX; NFI-X; Nuclear factor 1 X-type; Nuclear factor 1/A; Nuclear factor 1/B; Nuclear factor 1/C; nuclear factor 1/X; nuclear factor I X; Nuclear factor I/A; Nuclear factor I/B; Nuclear factor I/C; nuclear factor I/X; nuclear factor I/X (CCAAT-binding transcription factor); SOTOS2; TGGCA-binding protein
Gene Symbols NFIX
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 180-260 of human NFIX (NP_0024922).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18032, 4784
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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