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NFKB p100/p52 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980642
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50-198-0642 100 μL
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Catalog No. 50-198-0642 Supplier Bioss Supplier No. BS10037R
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Rabbit Polyclonal Antibody

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.

Specifications

Antigen NFKB p100/p52
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Nfkb2
Gene Accession No. Q00653
Gene Alias CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; LYT10; LYT-10; NF kappaB2; NF-kappaB2; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; Nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; Oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2
Gene Symbols Nfkb2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NFKB p52.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4791
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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