Invitrogen™ NFkB p52/p100 Monoclonal Antibody (16B2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA537802

Catalog No. PIMA537802

Description

Positive controls: Human tonsil tissue, human placenta tissue, A431 cell, Siha cell lysates.

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.

Specifications

• Antigen: NFkB p52/p100
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q00653
• Gene Symbols: Nfkb2
• Immunogen: Synthetic peptide within Human NFKB2 aa 1-50.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 16B2
• Conjugate: Unconjugated
• Gene: Nfkb2
• Gene Alias: CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; LYT10; LYT-10; NF kappaB2; NF KB; NF-kappaB2; nfkb p100; NF-kB p52/p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4791
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov