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NFKB1 Mouse anti-Human, Clone: 4D1, Abnova™

Catalog No. 89934691 Shop All Abnova Corporation Products
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89-934-691 50 μg
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Catalog No. 89-934-691 Supplier Abnova Corporation Supplier No. MAB12910
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Mouse monoclonal antibody raised against full length recombinant human NFKB1.

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen NFKB1
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone 4D1
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant human NFKB1.
Dilution Immunofluorescence Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.09% sodium azide).
Gene Alias DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NFKB-p105/NFKB-p50/p105/p50
Gene Symbols NFKB1
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human NFKB1.
Purification Method Affinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4790
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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