NFKB2 (phospho S866) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Catalog No.	Quantity
89-956-773	100 μL

Catalog No. 89-956-773 Supplier Abnova Corporation Supplier No. PAB29599

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NFKB2.

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM]

Specifications

• Antigen: NFKB2 (phospho S866)
• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NFKB2.
• Dilution: Immunofluorescence (1:100-1:200) Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: LYT-10/LYT10
• Gene Symbols: NFKB2
• Host Species: Rabbit
• Immunogen: A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S866 of human NFKB2.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4791
• Test Specificity: NFKB2 (phospho S866) polyclonal antibody detects endogenous level of NFKB2 only when phosphorylated at serine 866.
• Target Species: Human, Mouse, Rabbit
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid