Invitrogen™ NFKBID Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549695

Catalog No. PA549695

Description

The antibody detects endogenous level of total NFKBID protein.

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I-kappa-BNS, the nuclear I-kappa-B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I-kappa-BNS has been identified as a member of the I-kappa-B family of NF-kappa-B inhibitors, which undergoes induction upon TCR signaling. I-kappa-BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

Specifications

• Antigen: NFKBID
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFKBID
• Gene Alias: ikappaBdelta; I-kappa-B-delta; IkappaBNS; IkB-delta; IKBNS; NF-kappa B inhibitor; NF-kappa-B inhibitor delta; NFKB inhibitor delta; Nfkbid; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; TA-NFKBH; T-cell activation NFKB-like protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84807
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8NI38
• Gene Symbols: NFKBID
• Immunogen: Fusion protein corresponding to a region derived from 1-221 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG