Invitrogen™ NFKBIL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523499

Catalog No. PIPA523499

Description

Suggested positive control: HeLa. The amino acid sequence used as immunogen is 100% homologous in new world monkey, panda, mouse lemur, chimpanzee, orangutan, rhesus monkey, wild pig, 95% homologous in horse, rat, mouse, 89% homologous in frog, opossum, sea anemone and 74% homologous in platypus and carolina anole. Reacts with Frog. Immunogen sequence: RRYLRVQQVR WHPDRFLQR.

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.

Specifications

• Antigen: NFKBIL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFKBIL1
• Gene Alias: DADB-70P7.2; Def-7; ikappaBL; I-kappa-B-like protein; Ikbl; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKB inhibitor like 1; NFKBIL; NFKBIL1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100050027, 462558, 4795, 481711, 514369
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: Q861W0, Q9UBC1
• Gene Symbols: NFKBIL1
• Immunogen: Human NFKBIL1 (aa 331-349).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Monkey, Bovine, Horse, Amphibian, Chimpanzee
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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