Invitrogen™ NFKBIL1 Polyclonal Antibody

Catalog No.	Quantity
PIPA587914	100 μL

Catalog No. PIPA587914 Supplier Invitrogen™ Supplier No. PA587914

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSNPSPQVPE EEASTSVCRP KSSMASTSRR QRRERRFRRY LSAGRLVRAQ ALLQRHPGLD VDAGQPPPLH RACARHDAPA LCLLLRLGAD PAHQDRHGDT ALHAAARQGP DAYTDFFLPL LSRCPSAMGI KNKDGETPGQ ILGWGPPWDS AEEEEEDDAS KEREWRQKLQ GELEDEWQEV MGRFEGDASH ETQEPESFSA WSDRLAREHA QKCQQQQREA EGSRRPPRAE GSSQSWRQQE EEQRLFRERA RAKEEELRES RARRAQEALG DREPKPTRAG PREEHPRGAG RGSLWRFGDV PWPCPGGGDP EAMAAALVAR GPPLEEQGAL RRYLRVQQVR WHPDRFLQRF RSQIETWELG RVMGAVTALS QALNRHAEAL K; Positive Samples: U-87MG, HL-60, HepG2; Cellular Location: Nucleus.

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.

Specifications

• Antigen: NFKBIL1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 2.06 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NFKBIL1
• Gene Accession No.: Q9UBC1
• Gene Alias: DADB-70P7.2; Def-7; ikappaBL; I-kappa-B-like protein; Ikbl; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKB inhibitor like 1; NFKBIL; NFKBIL1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
• Gene Symbols: NFKBIL1
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_0049983).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4795
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG