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Invitrogen™ NFKBIL1 Polyclonal Antibody
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Catalog No. PIPA5103495
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100 μL
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PIPA5103495 100 μL
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Catalog No. PIPA5103495 Supplier Invitrogen™ Supplier No. PA5103495
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NFKBIL1.

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFKBIL1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NFKBIL1
Gene Accession No. O88995, Q8R2H1, Q9UBC1
Gene Alias DADB-70P7.2; Def-7; ikappaBL; I-kappa-B-like protein; Ikbl; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKB inhibitor like 1; NFKBIL; NFKBIL1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Gene Symbols NFKBIL1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NFKBIL1(Accession Q9UBC1), corresponding to amino acid residues Q108-D158.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18038, 361794, 4795
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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