Invitrogen™ NFKBIL2 Polyclonal Antibody

Catalog No.	Quantity
PIPA561245	100 μL

Catalog No. PIPA561245 Supplier Invitrogen™ Supplier No. PA561245

Description

Rabbit Polyclonal Antibody

Immunogen sequence: IRVRVQVQDH LFLIPVPHSS DTHSVAWLAE QAAQRYYQTC GLLPRLTLRK EGALLAPQDL IPDVLQSNDE VLAEVTSWDL PPLTDRYRRA CQSLGQGEHQ QVLQAVELQG LGLSFSACSL ALDQAQLTPL LRALKLHT Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 88%.

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Specifications

• Antigen: NFKBIL2
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TONSL
• Gene Accession No.: Q96HA7
• Gene Alias: DNA repair protein; ikappaBR; I-kappa-B-related protein; IKBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; NFKBIL2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; TONSL; tonsoku-like; Tonsoku-like protein; tonsoku-like, DNA repair protein
• Gene Symbols: TONSL
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human NFKBIL2. Recombinant protein control fragment (Product #RP-103689).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4796
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG