Invitrogen™ NFRKB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552389

Catalog No. PIPA552389

Description

Immunogen sequence: KSSSGVLLVS SPTMPHLGTM LSPASSQTAP SSQAAARVVS HSGSAGLSQV RVVAQPSLPA VPQQSGGPAQ TLPQMPAGPQ IRVPATATQT KVVPQTVMAT VPVKAQTTAA TV Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.

NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.

Specifications

• Antigen: NFRKB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFRKB
• Gene Alias: A530090G11Rik; DNA-binding protein R kappa B; DNA-binding protein R kappa-B; INO80 complex subunit G; INO80G; NFRKB; nuclear factor related to kappa B binding protein; nuclear factor related to kappaB binding protein; nuclear factor related to kappa-B-binding protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4798
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6P4R8
• Gene Symbols: NFRKB
• Immunogen: Recombinant protein corresponding to Human NFRKB. Recombinant protein control fragment (Product #RP-89400).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG