Invitrogen™ NFS1 Monoclonal Antibody (OTI5D1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526761

Catalog No. PIMA526761

Description

NFS1 Monoclonal Antibody for Western Blot, IHC (P)

NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family. It localizes to the cytoplasm or mitochondrion depending on which form is generated based on cytosolic pH. Highest expression levels of NFS1 are found in heart and skeletal muscle. Lower levels of expression are also found in liver, brain and pancreas. NFS1 is responsible for catalyzing the removal of sulfur from cysteine to form alanine, thereby supplying the inorganic sulfur for iron-sulfur (Fe-S) clusters. Fe-S clusters function as essential cofactors in a wide variety of events, including facilitation of electron transfer processes in oxidative phosphorylation, catalysis of enzymatic reactions in aconitase and dehydratases and maintenance of structural integrity in the DNA repair enzyme endonuclease III.

Specifications

• Antigen: NFS1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9Y697
• Gene Symbols: NFS1
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-299 of NFS1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5D1
• Conjugate: Unconjugated
• Gene: NFS1
• Gene Alias: AA987187; cysteine desulfurase, mitochondrial; Cysteine desulfurase, mitochondrial-like protein; HUSSY-08; IscS; LOW QUALITY PROTEIN: cysteine desulfurase, mitochondrial; m-Nfs1; m-Nfsl; Nfs1; NFS1 cysteine desulfurase; NFS1 nitrogen fixation 1 homolog; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1, cysteine desulfurase; Nifs; nifS-like (sic); nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen fixation gene 1; nitrogen fixation gene 1 (S. cerevisiae); nitrogen fixation gene, yeast homolog 1; nitrogen-fixing bacteria S-like protein
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9054
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid