NFX1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8510	100 μL

Catalog No. 50-198-8510 Supplier Bioss Supplier No. BS8377R

Description

Rabbit Polyclonal Antibody

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Specifications

• Antigen: NFX1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: NFX1
• Gene Accession No.: Q12986
• Gene Alias: 1300017N15Rik; 3000003M19Rik; BOS_9128; DKFZp779G2416; MGC20369; m-Nfx.1; NFX.1; Nfx1; NFX2; Nuclear transcription factor, X box-binding protein 1; nuclear transcription factor, X-box binding 1; TEG-42; testis expressed gene 42; Tex42; Transcriptional repressor NF-X1; X-box binding 1
• Gene Symbols: NFX1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human NFX1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4799
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG