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Invitrogen™ NFYB Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA575227
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold handshake motif in a manner analogous to the histone proteins H2B and H2A, respectively.
Specifications
NFYB | |
Polyclonal | |
Unconjugated | |
NFYB | |
AA985999; CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CBF-A; CBFB; CBF-B; CCAAT binding transcription factor of CBF-B/NFY-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; HAP3; nf-y; Nfya; Nfyb; NF-YB; nuclear transcription factor - Y beta; nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; nuclear transcription factor-Y beta; Transcription factor NF-Y, B subunit | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
18045, 25336, 4801 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
P25208, P63139, P63140 | |
NFYB | |
Synthetic peptide corresponding to the N-terminal of Human NFYB. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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