Invitrogen™ NFYB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575227

Catalog No. PIPA575227

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold handshake motif in a manner analogous to the histone proteins H2B and H2A, respectively.

Specifications

• Antigen: NFYB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFYB
• Gene Alias: AA985999; CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CBF-A; CBFB; CBF-B; CCAAT binding transcription factor of CBF-B/NFY-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; HAP3; nf-y; Nfya; Nfyb; NF-YB; nuclear transcription factor - Y beta; nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; nuclear transcription factor-Y beta; Transcription factor NF-Y, B subunit
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18045, 25336, 4801
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P25208, P63139, P63140
• Gene Symbols: NFYB
• Immunogen: Synthetic peptide corresponding to the N-terminal of Human NFYB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG