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Invitrogen™ NFYB Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA531913
Description
Recommended positive controls: HeLa, HeLa nuclear extract, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Pig (99%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold handshake motif in a manner analogous to the histone proteins H2B and H2A, respectively.
Specifications
NFYB | |
Polyclonal | |
Unconjugated | |
NFYB | |
AA985999; CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CBF-A; CBFB; CBF-B; CCAAT binding transcription factor of CBF-B/NFY-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; HAP3; nf-y; Nfya; Nfyb; NF-YB; nuclear transcription factor - Y beta; nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; nuclear transcription factor-Y beta; Transcription factor NF-Y, B subunit | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
18045, 25336, 4801 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
0.42 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
P25208, P63139, P63140 | |
NFYB | |
Recombinant fragment corresponding to a region within amino acids 33 and 207 of Human NFYB. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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