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Invitrogen™ NFYC Polyclonal Antibody
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Catalog No. PIPA536303
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100 μL
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PIPA536303 100 μL
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Catalog No. PIPA536303 Supplier Invitrogen™ Supplier No. PA536303
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Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 50 kDa. Purity is >95% by SDS-PAGE.

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold handshake motif in a manner analogous to the histone proteins, H2B and H2A, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFYC
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene NFYC
Gene Accession No. P70353, Q13952, Q62725
Gene Alias CAAT box DNA-binding protein subunit C; CAAT-box DNA-binding protein subunit C; CBFC; CBF-C; CCAAT binding factor of CBF-C/NFY-C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; CCAAT-binding transcription factor subunit C; DKFZp667G242; fb98f01; FLJ45775; H1TF2A; HAP5; histone H1 transcription factor large subunit 2A; HSM; NFYC; NF-YC; Nuclear transcription factor Y subunit C; nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; nuclear transcription factor-Y gamma; transactivator HSM-1; transactivator HSM-1/2; transcription factor NF-Y, C subunit; wu:fb98f01; zgc:55514
Gene Symbols NFYC
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 50-106 of human NF-YC.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18046, 25337, 4802
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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