Invitrogen™ NFYC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536303

Catalog No. PIPA536303

Description

This antibody detects endogenous protein at a molecular weight of 50 kDa. Purity is >95% by SDS-PAGE.

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold handshake motif in a manner analogous to the histone proteins, H2B and H2A, respectively.

Specifications

• Antigen: NFYC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFYC
• Gene Alias: CAAT box DNA-binding protein subunit C; CAAT-box DNA-binding protein subunit C; CBFC; CBF-C; CCAAT binding factor of CBF-C/NFY-C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; CCAAT-binding transcription factor subunit C; DKFZp667G242; fb98f01; FLJ45775; H1TF2A; HAP5; histone H1 transcription factor large subunit 2A; HSM; NFYC; NF-YC; Nuclear transcription factor Y subunit C; nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; nuclear transcription factor-Y gamma; transactivator HSM-1; transactivator HSM-1/2; transcription factor NF-Y, C subunit; wu:fb98f01; zgc:55514
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18046, 25337, 4802
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P70353, Q13952, Q62725
• Gene Symbols: NFYC
• Immunogen: Synthetic peptide corresponding to amino acids 50-106 of human NF-YC.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG