Invitrogen™ NFYC Polyclonal Antibody

Catalog No.	Quantity
PIPA565917	100 μL

Catalog No. PIPA565917 Supplier Invitrogen™ Supplier No. PA565917

Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQ Highest antigen sequence identity to the following orthologs - mouse 99%, rat 100%.

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold 'handshake' motif in a manner analogous to the histone proteins, H2B and H2A, respectively.

Specifications

• Antigen: NFYC
• Applications: ChIP Assay, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: NFYC
• Gene Accession No.: Q13952
• Gene Alias: CAAT box DNA-binding protein subunit C; CAAT-box DNA-binding protein subunit C; CBFC; CBF-C; CCAAT binding factor of CBF-C/NFY-C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; CCAAT-binding transcription factor subunit C; DKFZp667G242; fb98f01; FLJ45775; H1TF2A; HAP5; histone H1 transcription factor large subunit 2A; HSM; NFYC; NF-YC; Nuclear transcription factor Y subunit C; nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; nuclear transcription factor-Y gamma; transactivator HSM-1; transactivator HSM-1/2; transcription factor NF-Y, C subunit; wu:fb98f01; zgc:55514
• Gene Symbols: NFYC
• Host Species: Rabbit
• Immunogen: Recombinant Human NFYC. Recombinant protein control fragment (Product #RP-106594).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4802
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG