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Invitrogen™ NGB Polyclonal Antibody
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Catalog No. PIPA5110027
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100 μL
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PIPA5110027 100 μL
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Catalog No. PIPA5110027 Supplier Invitrogen™ Supplier No. PA5110027
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.

Globins are a superfamily of gas-binding heme proteins that are present in bacteria, protists, fungi, plants and animals. Globins play evolutionarily divergent roles which include binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide and carbon monoxide. Neuroglobin (Ngb) is a hexacoordinate hemoglobin that is predominantly expressed in the vertebrate brain and may enhance oxygen supply to neural components. Neuroglobin displays a high affinity for oxygen and its presence in cerebral neurons suggests a role in neuronal responses to hypoxia or ischemia. For example, in vitro neuronal hypoxia causes an elevation in the levels of neuroglobin, which enhances neuronal cell survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NGB
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NGB
Gene Accession No. Q9ER97, Q9NPG2
Gene Alias Neuroglobin; NGB
Gene Symbols NGB
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-151 of human NGB (NP_0670801).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58157, 64242
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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