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NGB Polyclonal Antibody, Invitrogen™

Catalog No. PIPA576950
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100 μL
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PIPA576950 100 μL
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Catalog No. PIPA576950 Supplier Thermo Scientific Supplier No. PA576950

Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Globins are a superfamily of gas-binding heme proteins that are present in bacteria, protists, fungi, plants and animals. Globins play evolutionarily divergent roles which include binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide and carbon monoxide. Neuroglobin (Ngb) is a hexacoordinate hemoglobin that is predominantly expressed in the vertebrate brain and may enhance oxygen supply to neural components. Neuroglobin displays a high affinity for oxygen and its presence in cerebral neurons suggests a role in neuronal responses to hypoxia or ischemia. For example, in vitro neuronal hypoxia causes an elevation in the levels of neuroglobin, which enhances neuronal cell survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NGB
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene NGB
Gene Accession No. Q99JA8, Q9ER97, Q9NPG2
Gene Alias Neuroglobin; NGB
Gene Symbols NGB
Host Species Rabbit
Immunogen Recombinant full length Human NGB.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58157, 64242, 85382
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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