Invitrogen™ NGF Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596054

Catalog No. PIPA596054

Description

Positive Samples: PC-3, SW480, PC-12, A375, A673, ES-2, MCF7, Mouse heart, Mouse brain; Cellular Location: Membrane, Single-pass type I membrane protein Immunogen sequence: LHSDSGISVD SQSLHDQQPH TQTASGQALK GDGGLYSSLP PAKREEVEKL LNGSAGDTWR HLAGELGYQP EHIDSFTHEA CPVRALLASW ATQDSATLDA.

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

Specifications

• Antigen: NGF Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ngfr
• Gene Alias: CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18053, 24596, 4804
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07174, P08138, Q9Z0W1
• Gene Symbols: Ngfr
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 301-400 of human p75NTR/NGFR (NP_0024981).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG