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Invitrogen™ NGFR Monoclonal Antibody (NGFR5), Biotin
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Catalog No. PIMA544090
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100 μg
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PIMA544090 100 μg
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Catalog No. PIMA544090 Supplier Invitrogen™ Supplier No. MA544090
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Description

Mouse Monoclonal Antibody

This antibody recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NGFR
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone NGFR5
Concentration 1 mg/mL
Conjugate Biotin
Formulation PBS with 15 mM sodium azide; pH 7.4
Gene Ngfr
Gene Accession No. P08138
Gene Alias CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16
Gene Symbols Ngfr
Host Species Mouse
Immunogen Purified CD271 protein isolated from human melanoma cell line A875.
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100349095, 101101519, 101680416, 4804
Target Species Human, Rabbit, Monkey, Feline, Ferret
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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