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Tocris Bioscience™ NGI 1
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Catalog No. 665225
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25 mg
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Catalog No. Quantity
66-522-5 25 mg
66-525 5 mg
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Catalog No. 66-522-5 Supplier Tocris Bioscience™ Supplier No. 6652/25
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Description

Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral

NGI 1 is an oligosaccharyltransferase (OST) inhibitor; anti-flaviviral. Inhibits dengue, Zika, West Nile, and yellow fever viruses by blocking viral RNA replication (EC50 values are 0.85 and 2.2 μM for DENV and ZIKV inhibition, respectively). Selectively arrests proliferation of non-small-cell lung cancer cells that are dependent on EGFR or FGFR for survival.

Specifications

Chemical Name or Material 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide
CAS 790702-57-7
Quantity 25 mg
Target Other Transferase Inhibitors
Molecular Formula C17H22N4O3S2
Formula Weight 394.51
Purity 98%
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