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Tocris Bioscience™ NGI 1
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Catalog No. 66525 Shop All Novus Biologicals Products
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66-525 5 mg
66-522-5 25 mg
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Catalog No. 66-525 Supplier Tocris Bioscience™ Supplier No. 6652/5
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Description

Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral

NGI 1 is an oligosaccharyltransferase (OST) inhibitor; anti-flaviviral. Inhibits dengue, Zika, West Nile, and yellow fever viruses by blocking viral RNA replication (EC50 values are 0.85 and 2.2 μM for DENV and ZIKV inhibition, respectively). Selectively arrests proliferation of non-small-cell lung cancer cells that are dependent on EGFR or FGFR for survival.

Specifications

Chemical Name or Material 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide
CAS 790702-57-7
Quantity 5 mg
Target Other Transferase Inhibitors
Molecular Formula C17H22N4O3S2
Formula Weight 394.51
Purity 98%
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