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Nicastrin Polyclonal Antibody, Invitrogen™

Catalog No. PIPA585427
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100 μL
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PIPA585427 100 μL
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Catalog No. PIPA585427 Supplier Thermo Scientific Supplier No. PA585427

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: 293T, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nicastrin
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene NCSTN
Gene Accession No. Q92542
Gene Alias APH2 antibody; KIAA0253 antibody; NCSTN antibody; nicastrin antibody; anterior pharynx-defective 2 antibody; ATAG1874 antibody
Gene Symbols NCSTN
Host Species Rabbit
Immunogen Recombit protein encompassing a sequence within the center region of human Nicastrin.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23385
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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