Nicotinamide, 99%

Description

CAS: 98-92-0 | C6H6N2O | 122.127 g/mol

Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

Solubility
Soluble in water, ethanol , glycerol, DMSO , methanol, butanol and chloroform. Slightly soluble in ether.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 98-92-0
• Molecular Formula: C6H6N2O
• Molecular Weight (g/mol): 122.127
• MDL Number: MFCD00006395
• InChI Key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
• Synonym: nicotinamide, niacinamide, 3-pyridinecarboxamide, vitamin pp, nicotinic acid amide, papulex, aminicotin, amixicotyn, nicobion, nicotylamide
• PubChem CID: 936
• ChEBI: CHEBI:17154
• IUPAC Name: pyridine-3-carboxamide
• SMILES: C1=CC(=CN=C1)C(=O)N

• Melting Point: 128°C to 132°C
• Density: 1.4
• Flash Point: 182°C (360°F)
• Assay Percent Range: 99%
• Quantity: 250 g
• Beilstein: 383619
• Merck Index: 14,6523
• Solubility Information: Soluble in water,ethanol ,glycerol,DMSO ,methanol,butanol and chloroform. Slightly soluble in ether.
• Formula Weight: 122.13
• Percent Purity: 99%
• Chemical Name or Material: Nicotinamide

Safety and Handling

Hazard Category	H319-H500
Hazard Statement	GHS H Statement H319
Precautionary Statement	P264b-P280i-P305+P351+P338
EINECSNumber	202-713-4
RTECSNumber	QS3675000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only