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Invitrogen™ Nidogen G1 Domain Monoclonal Antibody (JF3)
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Catalog No. PIMA517018
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100 μL
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Catalog No. Quantity
PIMA517018 100 μL
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Catalog No. PIMA517018 Supplier Invitrogen™ Supplier No. MA517018
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Description

Rat Monoclonal Antibody

MA5-17018 recognizes native and denatured mouse and human nidogen, and blocks binding of nidogen to laminin. MA5-17018 has been successfully used in ELISA and Western blot applications. The MA5-17018 immunogen is a recombinant fragment corresponding to the G1Link region of mouse nidogen produced in Fisher rat plus YB2/0 cells.

Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Although the precise composition and structure of basal laminae varies from tissue to tissue, as well as within the same tissue at different developmental stages, most mature basal laminae contain type IV collagen, laminins, heparan sulphate proteoglycans and entactin (or nidogen). Entactin is a sulfated glycoprotein that is widely distributed in basement membranes. It is tightly associated with laminin and also binds to collagen IV. Entactin probably has a role in cell-extracellular matrix interactions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nidogen G1 Domain
Applications ELISA, Western Blot, Western Blot
Classification Monoclonal
Clone JF3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.5M acetic acid, 2M tris with 0.1% sodium azide
Gene NID1
Gene Accession No. P10493, P14543
Gene Alias A630025O17; enactin; Ent; Entactin; entactin 1; entactin-1; NID; NID 1; Nid1; NID-1; Nidogen (enactin); nidogen 1; Nidogen precursor (Entactin); nidogen-1
Gene Symbols NID1
Host Species Rat
Immunogen Recombinant fragment corresponding to the G1Link region of mouse nidogen produced in Fisher rat plus YB2/0 cells.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18073, 4811
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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