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Invitrogen™ Nidogen G2 Domain Monoclonal Antibody (JF4)
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Catalog No. PIMA517017
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50 μL
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Catalog No. Quantity
PIMA517017 50 μL
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Catalog No. PIMA517017 Supplier Invitrogen™ Supplier No. MA517017
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Description

Rat Monoclonal Antibody

MA5-17017 recognizes native and denatured mouse and human nidogen, and blocks binding of nidogen to laminin. MA5-17017 has been successfully used in ELISA and Western blot applications. The MA5-17017 immunogen is a recombinant fragment corresponding to the G2 region of mouse nidogen produced in Fisher rat plus YB2/0 cells.

Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Although the precise composition and structure of basal laminae varies from tissue to tissue, as well as within the same tissue at different developmental stages, most mature basal laminae contain type IV collagen, laminins, heparan sulphate proteoglycans and entactin (or nidogen). Entactin is a sulfated glycoprotein that is widely distributed in basement membranes. It is tightly associated with laminin and also binds to collagen IV. Entactin probably has a role in cell-extracellular matrix interactions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nidogen G2 Domain
Applications ELISA, Inhibition Assays, Western Blot
Classification Monoclonal
Clone JF4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.5M acetic acid, 2M tris with 0.1% sodium azide
Gene NID1
Gene Accession No. P10493, P14543
Gene Alias A630025O17; enactin; Ent; Ent 2; entactin; entactin 1; Entactin 2; entactin-1; NID; NID 2; NID1; NID-1; Nid2; Nidogen (enactin); nidogen 1; Nidogen 2; Nidogen precursor (Entactin); nidogen-1
Gene Symbols NID1
Host Species Rat
Immunogen Recombinant fragment corresponding to the G2 region of mouse nidogen produced in Fisher rat plus YB2/0 cells.
Purification Method Protein G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18073, 4811
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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