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Invitrogen™ NIK Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA141320
Description
Suggested positive control: antigen standard for MAP3K14 (transient overexpression lysate).
MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Specifications
NIK | |
Polyclonal | |
Unconjugated | |
MAP3K14 | |
aly; alymphoplasia; FTDCR1B; HS; HsNIK; Map3k14; Mitogen-activated protein kinase kinase kinase 14; NF kappa B-inducing kinase; NF-kappa-beta-inducing kinase; Nfkb inducing kinase; NIK; protein kinase; serine/threonine-protein kinase NIK | |
Rabbit | |
Protein G | |
RUO | |
9020 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with no preservative | |
Q99558 | |
MAP3K14 | |
Synthetic peptide corresponding to residues 687-703 of human NIK. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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