Invitrogen™ NIPA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554954

Catalog No. PIPA554954

Description

Immunogen sequence: IQVHVTACIL SVCGWACSSS LESMQLSLIT CSQCMRKVGL WGFQQIESSM TDLDASFGLT SSPIPGLEGR PERLPLVPES PRRMMTRSQD Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

Specifications

• Antigen: NIPA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZC3HC1
• Gene Alias: 1110054L24Rik; AU018540; AU019789; C3HC type 1; hematopoietic stem/progenitor cell protein 216; hNIPA; HSPC216; mNIPA; Nipa; nuclear interacting partner of ALK; nuclear interacting partner of anaplastic lymphoma kinase (Alk); nuclear-interacting partner of ALK; Nuclear-interacting partner of anaplastic lymphoma kinase; OTTHUMP00000212330; RGD1561099; ZC3HC1; zinc finger C3HC-type containing 1; zinc finger C3HC-type protein 1; zinc finger, C3HC type 1; zinc finger, C3HC-type 1; zinc finger, C3HC-type containing 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 232679, 296957, 51530
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q80YV2, Q86WB0
• Gene Symbols: ZC3HC1
• Immunogen: Recombinant protein corresponding to Human NIPA. Recombinant protein control fragment (Product #RP-92633).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG