Invitrogen™ NIPSNAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563688

Catalog No. PIPA563688

Description

Immunogen sequence: EYLDAYNSLT EAVLPKLHLD EDYPCSLV Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

Specifications

• Antigen: NIPSNAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NIPSNAP1
• Gene Alias: 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans); nipsnap homolog 1 (C. elegans); Nipsnap1; Protein NipSnap homolog 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8508
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BPW8
• Gene Symbols: NIPSNAP1
• Immunogen: Recombinant protein corresponding to Human NIPSNAP1. Recombinant protein control fragment (Product #RP-101842).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG