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Invitrogen™ NIT1 Polyclonal Antibody
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Catalog No. PIPA552317
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100 μL
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Catalog No. Quantity
PIPA552317 100 μL
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Catalog No. PIPA552317 Supplier Invitrogen™ Supplier No. PA552317
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FLSLLCPGLR IPQLSVLCAQ PRPRAMAISS SSCELPLVAV CQVTSTPDKQ QNFKTCAELV REAARLGACL AFLPEAFDFI ARDPAETLHL SEPLGGKLLE EYTQLARECG LWLSLGGFHE RGQDWEQT Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 67%.

Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NIT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NIT1
Gene Accession No. Q86X76
Gene Alias AI255805; Deaminated glutathione amidase; dGSH amidase; ESTM30; MGC57670; Nit1; nitrilase 1; nitrilase homolog 1; rCG_20134; W57327
Gene Symbols NIT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NIT1. Recombinant protein control fragment (Product #RP-89178).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4817
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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