Invitrogen™ NIT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552317

Catalog No. PIPA552317

Description

Immunogen sequence: FLSLLCPGLR IPQLSVLCAQ PRPRAMAISS SSCELPLVAV CQVTSTPDKQ QNFKTCAELV REAARLGACL AFLPEAFDFI ARDPAETLHL SEPLGGKLLE EYTQLARECG LWLSLGGFHE RGQDWEQT Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 67%.

Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.

Specifications

• Antigen: NIT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NIT1
• Gene Alias: AI255805; Deaminated glutathione amidase; dGSH amidase; ESTM30; MGC57670; Nit1; nitrilase 1; nitrilase homolog 1; rCG_20134; W57327
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4817
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86X76
• Gene Symbols: NIT1
• Immunogen: Recombinant protein corresponding to Human NIT1. Recombinant protein control fragment (Product #RP-89178).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG