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Invitrogen™ NKCC1 Polyclonal Antibody
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Catalog No. PIPA533023
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50 μg
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Catalog No. Quantity
PIPA533023 50 μg
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Catalog No. PIPA533023 Supplier Invitrogen™ Supplier No. PA533023
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon (89%) Monkey, Marmoset, Ferret, Dog, Panda (84%).

NKCC1 mediates sodium and chloride transport and reabsorption. NKCC1 is a membrane protein and is important in maintaining proper ionic balance and cell volume. NKCC1 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, NKCC1 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for NKCC1. Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKCC1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene SLC12A2
Gene Accession No. P55011
Gene Alias 9330166H04Rik; basolateral NaK(2Cl) cotransporter; basolateral Na-K-Cl symporter; BSC; BSC2; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; little ears; lte; mBSC2; Na-K-2Cl- cotransporter; Na-K-Cl cotransporter; NKCC1; PPP1R141; protein phosphatase 1, regulatory subunit 141; Slc12a2; slc12a4; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (potassium/chloride transporters), member 2; solute carrier family 12 (potassium/chloride transporters), member 4; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; solute carrier family 12 member 2; solute carrier family 12, member 2; sy-ns; zfnkcc1; zgc:85961; zmp:0000000537
Gene Symbols SLC12A2
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from N-terminus of human SLC12A2 / NKCC1.
Purification Method Antigen Affinity Chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6558
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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