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NKG2A/B + NKG2C + NKG2E + NKG2F Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984709
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100 μL
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50-198-4709 100 μL
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Catalog No. 50-198-4709 Supplier Bioss Supplier No. BS2416R
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Rabbit Polyclonal Antibody

Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.

Specifications

Antigen NKG2A/B + NKG2C + NKG2E + NKG2F
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene KLRC2
Gene Accession No. O43908, P26715, P26717, Q07444
Gene Symbols KLRC1, KLRC2, KLRC3, KLRC4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NKG2C.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3821, 3822, 3823, 8302
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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