Invitrogen™ NKG2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588485

Catalog No. PIPA588485

Description

Immunogen sequence: RHCGHCPEEW ITYSNSCYYI GKERRTWEES LLACTSKNSS LLSIDNEEEM KFLSIISPSS WIGVFRNSSH HPWVTMNGLA FKHEIKDSDN AELNCAVLQV NRLKSAQCGS SIIYHCKHKL; Positive Samples: Mouse testis, Mouse liver; Cellular Location: Membrane, Single-pass type II membrane protein.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Specifications

• Antigen: NKG2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klrc1
• Gene Symbols: Klrc1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_0155671).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 0.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CD159 antigen-like family member A; CD159A; C-lectin type II protein; Cluster of Differentiation 159a; killer cell lectin like receptor C1; killer cell lectin-like receptor subfamily C, member 1; Klrc1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; rNKG2A
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16641
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid