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Invitrogen™ NKG2A Polyclonal Antibody
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Catalog No. PIPA5115482
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100 μL
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PIPA5115482 100 μL
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Catalog No. PIPA5115482 Supplier Invitrogen™ Supplier No. PA5115482
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KLRC1.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKG2A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Klrc1
Gene Accession No. P26715
Gene Alias CD159 antigen-like family member A; CD159A; C-lectin type II protein; Cluster of Differentiation 159a; killer cell lectin like receptor C1; killer cell lectin-like receptor subfamily C, member 1; Klrc1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; rNKG2A
Gene Symbols Klrc1
Host Species Rabbit
Immunogen A synthesized peptide derived from human KLRC1(Accession P26715), corresponding to amino acid residues M1-Y40.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3821
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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