Invitrogen™ NKG2C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566127

Catalog No. PIPA566127

Description

Immunogen sequence: CAVLQVNRLKS AQCGSSMIYH CKH Highest antigen sequence identity to the following orthologs - mouse 38%, rat 38%.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Specifications

• Antigen: NKG2C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLRC2
• Gene Alias: CD159 antigen-like family member C; CD159A; CD159c; cd159e; killer cell lectin like receptor C2; killer cell lectin-like receptor subfamily C, member 2; KLRC1; KLRC2; NK cell receptor C; NKG2; NKG2A; NKG2C; NKG2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3822
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.08 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P26717
• Gene Symbols: KLRC2
• Immunogen: Recombinant Human NKG2C. Recombinant protein control fragment (Product #RP-105632).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov