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Invitrogen™ NKG2C Polyclonal Antibody
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Catalog No. PIPA528837
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100 μL
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PIPA528837 100 μL
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Catalog No. PIPA528837 Supplier Invitrogen™ Supplier No. PA528837
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: K562. Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKG2C
Applications Western Blot
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene KLRC2
Gene Accession No. P26717
Gene Alias CD159 antigen-like family member C; CD159A; CD159c; cd159e; killer cell lectin like receptor C2; killer cell lectin-like receptor subfamily C, member 2; KLRC1; KLRC2; NK cell receptor C; NKG2; NKG2A; NKG2C; NKG2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor
Gene Symbols KLRC2
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of human NKG2-C. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3822
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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