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  6. NKG2D/CD314 Antibody (1D11) - Low Endotoxin, Azide and BSA Free, Novus Biologicals™

NKG2D/CD314 Antibody (1D11) - Low Endotoxin, Azide and BSA Free, Novus Biologicals™
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Catalog No. p-7199565 Shop All R&D Systems Products
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0.25 mg
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Catalog No. Quantity
NB017762 0.05 mg
NB10065956 0.25 mg
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Catalog No. NB017762 Supplier Novus Biologicals Supplier No. NB100659560.05MG
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Description

Mouse Monoclonal Antibody has been used in 3 publications

NKG2D/CD314 Monoclonal specifically detects NKG2D/CD314 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready, Functional Assay.

Specifications

Antigen NKG2D/CD314
Applications Immunohistochemistry (Frozen), Functional Assay, CyTOF, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone 1D11
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay
Formulation Phosphate buffered saline with No Preservative
Gene Accession No. P26718
Gene Alias CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Gene Symbols KLRK1
Host Species Mouse
Immunogen NKL cells.
Purification Method Protein A purified
Quantity 0.05 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22914
Test Specificity NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Target Species Human
Content And Storage Store at -20C. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1
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