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Invitrogen™ NKG2D Monoclonal Antibody (1D11), FITC
Mouse Monoclonal Antibody
Supplier: Invitrogen™ A15760

Description
This antibody recognizes an extracellular epitope of CD314 / NKG2D, a 42 kDa C-type lectin-like activating receptor expressed by NK cells, gamma/delta T cells, and CD8+ T cells.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
Specifications
NKG2D | |
Monoclonal | |
FITC | |
Klrk1 | |
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D | |
Mouse | |
Size-exclusion chromatography | |
RUO | |
22914 | |
4°C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
1D11 | |
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4 | |
P26718 | |
Klrk1 | |
NKL cell line. | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
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