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Invitrogen™ NKG2D Monoclonal Antibody (1D11), FITC
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Catalog No. 501137752
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100 Tests
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50-113-7752 100 Tests
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Catalog No. 50-113-7752 Supplier Invitrogen™ Supplier No. A15760
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Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope of CD314 / NKG2D, a 42 kDa C-type lectin-like activating receptor expressed by NK cells, gamma/delta T cells, and CD8+ T cells.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKG2D
Applications Flow Cytometry
Classification Monoclonal
Clone 1D11
Conjugate FITC
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Klrk1
Gene Accession No. P26718
Gene Alias CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Gene Symbols Klrk1
Host Species Mouse
Immunogen NKL cell line.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22914
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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