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Invitrogen™ NKG2D Polyclonal Antibody
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Catalog No. PIPA5109890
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100 μL
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PIPA5109890 100 μL
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Catalog No. PIPA5109890 Supplier Invitrogen™ Supplier No. PA5109890
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VFLNSLFNQE VQIPLTESYC GPCPKNWICY KNNCYQFFDE SKNWYESQAS CMSQNASLLK VYSKEDQDLL KLVKSYHWMG LVHIPTNGSW QWEDGSILSP NLLTIIEMQK GDCALYASSF KGYIENCSTP NTYICMQRTV.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKG2D
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Klrk1
Gene Accession No. O54709, P26718
Gene Alias CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Gene Symbols Klrk1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 77-216 of human KLRK1 (NP_031386.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22914, 27007
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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