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NKIRAS1 Monoclonal Antibody (OTI6C11), TrueMAB™, OriGene

Mouse Monoclonal Antibody
Supplier: OriGene TA505394

Description
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.Specifications
NKIRAS1 | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q9NYS0 | |
NKIRAS1 | |
Full length human recombit protein of human NKIRAS1 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI6C11 | |
Unconjugated | |
NKIRAS1 | |
KBRAS1, kappaB-Ras1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
28512 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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