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NKIRAS1 Mouse anti-Human, Clone: OTI6C11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF505394

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.Specifications
NKIRAS1 | |
Monoclonal | |
Unconjugated | |
NKIRAS1 | |
KBRAS1, kappaB-Ras1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
28512 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI6C11 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9NYS0 | |
NKIRAS1 | |
Full length human recombit protein of human NKIRAS1 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2b |
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