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Invitrogen™ Nkx2.1 Monoclonal Antibody (8G7G3/1)
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Catalog No. PIMA513961
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500 μL
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PIMA513961 500 μL
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Catalog No. PIMA513961 Supplier Invitrogen™ Supplier No. MA513961
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Description

Mouse Monoclonal Antibody

MA5-13961 targets Thyroid Transcription Factor 1 in IF and IHC (P) applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13961 immunogen is rat TTF-1 recombinant protein.

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx2.1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 8G7G3/1
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene NKX2-1
Gene Accession No. P23441, P43699, P50220
Gene Alias AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1
Gene Symbols NKX2-1
Host Species Mouse
Immunogen Rat TTF-1 recombinant protein.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21869, 25628, 7080
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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