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Invitrogen™ Nkx2.5 Monoclonal Antibody (4B11)
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Catalog No. PIMA518671
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100 μg
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Catalog No. Quantity
PIMA518671 100 μg
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Catalog No. PIMA518671 Supplier Invitrogen™ Supplier No. MA518671
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Mouse Monoclonal Antibody

Peptide Sequence: MFPSPALTPT PFSVKDILNL EQQQRSLAAA GELSARLEAT LAPSSCMLAA FKPEAYAGPE AAAPGLPELR AELGRAPSPA KCASAFPAAP AFYPRAYSDP DPAKDPRAEK KELCALQKAV ELEKTEADNA *.

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx2.5
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 4B11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Nkx2-5
Gene Accession No. P52952
Gene Alias Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; NKX2-5; NKX2E; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3
Gene Symbols Nkx2-5
Host Species Mouse
Immunogen NKX2-5 (NP_004378, 1 a.a. ~ 130 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1482
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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