Invitrogen™ Nkx2.5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595225

Catalog No. PIPA595225

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Mouse Spleen Tissue, Mouse Cardiac Muscle Tissue, HELA whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Nkx2.5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nkx2-5
• Gene Alias: Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; NKX2-5; NKX2E; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1482, 18091
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P42582, P52952
• Gene Symbols: Nkx2-5
• Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Nkx2.5 (103-132aa AKDPRAEKKELCALQKAVELEKTEADNAER).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG