Invitrogen™ Nkx2.5 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519138

Catalog No. PIPA519138

Description

This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Nkx2.5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nkx2-5
• Gene Alias: Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; NKX2-5; NKX2E; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 114109, 1482, 18091
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O35767, P42582, P52952
• Gene Symbols: Nkx2-5
• Immunogen: Synthetic peptide sequence (PRAYSDPDPAKDPR) corresponding to the internal amino acids of NKX2-5 (aa 94-107).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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