Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5101642

Invitrogen™ Nkx2.6 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5101642
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5101642 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5101642 Supplier Invitrogen™ Supplier No. PA5101642
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NKX26.

Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and pancreas.Nkx-2.5, also designated cardiac specific homeobox protein (Csx), is a homolog of the Drosophila tinman protein and is essential for normal cardiovascular development. Expression of Nkx-2.5 during cardiomyogenesis is required for cardiac septation, in which a single atrium and ventricle are separated into four chambers. Nkx-2.5 binds to DNA as a monomer, a homodimer or as a heterodimer with Nkx-2.3 or Nkx-2.6, which suggests that the specific protein-protein interactions of Nkx-2.5 are involved in its transcriptional regulatory function. Nkx-2.6, also a homolog of the Drosophila tinman protein, is expressed in the caudal pharyngeal pouches,the caudal heart progenitors, the sinus venosus, the outflow tract of the heart and in a short segment of the gut between stages E8.5 and E10.5 of embryogenesis. Expression of Nkx-2.6 overlaps with that of Nkx-2.5 in the pharynx and heart. However, Nkx-2.6 mutant mice are viable and fertile, which suggests that Nkx-2.6 plays a compensatory function to Nkx-2.5.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx2.6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NKX2-6
Gene Accession No. A6NCS4
Gene Alias AV044928; CSX2; CTHM; Drosophila NK2 transcription factor related, locus 6; homeobox protein NK2 homolog F; homeobox protein NK-2 homolog F; homeobox protein NKX2.6; homeobox protein Nkx-2.6; NK2 homeobox 6; NK2 transcription factor related, locus 6; Nkx2.6; Nkx-2.6; Nkx2-6; Nkx2f; NKX4-2; tinman; tinman paralog; Tix
Gene Symbols NKX2-6
Host Species Rabbit
Immunogen A synthesized peptide derived from human NKX2-6(Accession A6NCS4), corresponding to amino acid residues G224-A274.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 137814
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.